产品货号：
Z28002
中文名称：
TIM3/HAVCR2抗体
英文名称：
Anti-TIM3/HAVCR2 Antibody
产品规格：
0.1mg
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-TIM3/HAVCR2 Antibody |
| 指标别名 | CD366;HAVcr 2;HAVCR2;KIM 3;T cell membrane protein 3;Tim 3;TIM3;TIM-3;TIMD 3;TIMD3 |
| 克隆性 | Polyclonal |
| 检验物种 | human |
| 应用范围 | ELISA,WB,IHC,IF |
| 基因名称 | HAVCR2 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | TIM-3 antibody was raised against a peptide corresponding to 16 amino acids near the amino terminus of human TIM-3.The immunogen is located within amino acids 60 - 110 of TIM-3. |
| 计算分子量 | 33kDa |
| 成分 | TIM-3 Antibody is supplied in PBS containing 0.02% sodium azide. |
| 纯化方式 | TIM-3 Antibody is affinity chromatography purified via peptide column. |
| 浓度 | 1mg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 4℃可保存3个月，-20℃可保存1年。 |
| 背景资料 | The immune checkpoint protein TIM-3 is a member of the immunoglobulin superfamily and TIM family of proteins that was initially identified as a specific marker of fully differentiated IFN-污producing CD4 T helper 1 (Th1) and CD8 cytotoxic cells.It is a Th1-specific cell surface protein that regulates macrophage activation and negatively regulates Th1-mediated auto- and alloimmune responses,and is also highly expressed on regulatory T cells,monocytes,macrophages,and dendritic cells (1).TIM-3 and PD-1 are co-expressed on most CD4 and CD8 T cells infiltrating solid tumors or in hematologic malignancy in mice;blocking TIM-3 in conjugation with a PD-1 blockade increases the functionality of exhausted T cells and synergizes with to inhibit tumor growth (2,3). |
| Uniprot ID | Q8TDQ0 |
| 基因名全称 | Hepatitis A virus cellular receptor 2 |
| 蛋白名全称 | Hepatitis A virus cellular receptor 2 |
| 推荐稀释比 | TIM-3 antibody can be used for Western blot at 1 ～ 2μg/mL.Antibody can also be used for Immunohistochemistry at 2μg/mL.For Immunoflorescence start at 20μg/mL.Antibody validated:Western Blot in human samples;Immunohistochemistry in human samples and Immunofluorescence in human samples.All other applications and species not yet tested. |
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